I understand it’s being misused by people who don’t need it, particularly in the entertainment industry. But I’m almost 400 lbs and my eating is worse than it’s ever been and I’m just in desperate need to rid myself of this obsession with always eating more no matter what. Does anyone here have any experience with it? I’ve heard it just works by making you nauseous but I’ve read elsewhere that that’s just a common side effect. At this point I’m nauseous most of the time anyway.

  • Lyudmila [she/her, comrade/them]@hexbear.net
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    5 days ago

    To be honest, the average layperson’s understanding of biology unfortunately becomes entirely useless and often counterproductive to having a useful understanding of pharmacology. You start talking about agonists and inhibitors and half the time common sense becomes actively detrimental to understanding and the peak of scientific knowledge is “we have no idea why or how this shit works, only that it does. Check back in with us in 10-30 years and maybe we’ll know like 20% more of an answer.”

    You find a binding site that does some shit and you slap an inhibitor on that bad boy and suddenly all your lab rats are jacked. Then like 15 years later someone else accidentally finds a single antibody doing some weird shit and you start cloning it, and hey what the fuck jacked rats again? What if we make this into a muscular dystrophy gene therapy drug?

    Then like another 10 years later somebody connects a couple dots between that old abandoned muscular dystrophy gene therapy drug and a weight loss drug and here we go!