I tend to use DuckDuckGo most of the time, but its quality has collapsed considerably. Google is terrible now and only worth it for reverse image search. I haven’t tried Brave much and SearX-NG was a pain to set up for being a de-facto Google and Bing wrapper. There’s Kagi but I don’t really have $120/yr for a search engine, nor do I want to deal with how they handle logins and session management.
There’s some little differences - for example, Qwant doesn’t spam you with irrelevant “Apple Maps” results on every search, as DDG has for a few years.